
产品货号:
Z32943
中文名称:
AHNAK Purified抗体
英文名称:
Anti-AHNAK Purified Antibody (Clone#EM-09)
产品规格:
0.1mg(C100)
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-AHNAK Purified Antibody (Clone#EM-09) |
指标别名 | AHNAK,AHNAK nucleoprotein,AHNAKRS,Desmoyokin,PM227 |
克隆性 | Monoclonal |
检验物种 | human,mouse |
应用范围 | WB,IHC-F,ICC,IP |
基因名称 | AHNAK |
克隆号 | EM-09 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Bacterially expressed fragment of N-terminal domain of human AHNAK1.The mouse monoclonal antibody EM-09 reacts with AHNAK1,a 700kDa multi-functional adaptor protein expressed mainly in epithelial cell,various types of muscle cells and immune cells. |
计算分子量 | 629kDa |
成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
纯化方式 | Purified by protein-A affinity chromatography. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | Store at 2~8℃.Do not freeze. |
背景资料 | AHNAK1 (Desmoyokin) is a large (700kDa) scaffold protein that translocates to the plasma membrane after an increas of extracellular calcium level or upon proteinkinase C activation and regulates extracellular calcium influx mediated by L-type Ca2+ channels.AHNAK1 has been implicated in diverse signal transduction proceses affecting cell differentiation and proliferation.In response to calcium-dependent intercellular contacts AHNAK1 forms multimeric complexes in the plasma membrane,connected with actin and annexin 2/S100A10 assemblies and is thus involved in organization of the plasma membrane architecture.In epithelial cells,AHNAK1 is localized in cytoplasm or is membrane-associated,but in cells of nonepithelial origin AHNAK1 is predominantly nuclear;it has a weak DNA-binding activity and associates with the DNA-ligase IV-XRCC4 complex. |
Uniprot ID | Q09666 |
基因名全称 | AHNAK1 nucleoprotein |
蛋白名全称 | Neuroblast differentiation-associated protein AHNAK |
推荐稀释比 | Immunocytochemistry:Positive control:HeLa human cervix carcinoma cell line,permeabilization is required. Western blotting:Positive control:HeLa human cervix carcinoma cell line. |
相关搜索:AHNAK Purified抗体,AHNAK Purified单抗,Anti-AHNAK Purified Antibody (Clone#EM-09)